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is a weekly newsmagazine which covers important research findings in all fields of science and medicine, with stories that appeal to both scientists and laymen. Save 68% lowest rate.

TIME Magazine, June 27, 1949, p. 66:

MEDICINE: Frontal Attack (cover story)
    ...Gangster Cells. The "cancer problem," as pathologists call it, is one of the strangest and subtlest that medicine has faced. Cancer is not an outside enemy that can be fought in the open like a foreign invader. It is a civil war among the body's own cells, and it runs through all of nature like a red fiber of ruin spun into the thread of life. All vertebrates, including frogs and fish, get cancer. In all probability, the experts say, invertebrates and plants have cancer too.

    As a normal thing, the several hundred trillion cells in a human body cooperate loyally, subordinating themselves to the body's higher life. Their functioning and their usually slow rate of multiplication are controlled, most scientists believe, by the chemical hormones which are poured into the blood by a set of regulating glands.

    Sometimes, for reasons which medicine does not yet understand, a cell turns out to be different from normal cells. Most such "mutations," less competent than the normal cells, die and are absorbed by the body. But occasionally a variant cell appears that is disastrously competent. Something in its chemistry allows it to defy the hormones that regulate the growth of ordinary cells. It multiplies wildly, growing into a useless mass of disorderly tissue. The tumor pushes among the normal cells, presses on nerves, thrusts organs aside or invades them. Often the gangster cells get into the blood and spread around the body like seeds carried by the wind. Where they lodge they grow into "metastases"--secondary tumors as lawless as the first one.

    That is cancer: war between the body and its rebel cells. But it is not a two sided civil war, because the body has no defenses. The body creates no antibodies against cancer as it does against diphtheria or typhoid. It builds no tissue walls to confine the destructive cells. It feeds them well, allows them to grow unchecked, and dies helplessly when they disrupt some vital function...
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